Mammalian Coronin 7
Authors
Journal
Title
PMID
Main point related to coronin
McCrary..Janssen 2026
J. Biol. Chem. (2026) 302:111258
Domain-selective folding of the tandem β-propeller protein Coronin 7 by the chaperonin CCT/TRiC
Analysis of the interaction of coronin 7 with the folding chaperones CCT/TRiC
Nejad..Dominguez 2025
Nat. comm. Nature Communications 16:9809
Mechanism of Arp2/3 complex branch
disassembly by human Coro7
Analysis of Arp2/3 complex-mediated branching by coronin 7
Inserra..Gobbi 2022
Prog Neuropsychopharmacol Biol Psychiatry (2022) 119:110594
Modulation of DNA methylation and protein expression in the prefrontal cortex by repeated administration of D-lysergic acid diethylamide (LSD): Impact on neurotropic, neurotrophic, and neuroplasticity signaling
Analyses of the effects of repeated lysergic acid diethylamide (LSD) on whole-genome DNA methylation and protein expression in the mouse prefrontal cortex (PFC), and reports that coronin 7 is among the genes that are differentially methylated and expressed, and that their transcription was increased
Hegazi..Cheng 2022
Nat Commun (2022) 13:1594
UBR4/POE facilitates secretory trafficking to maintain circadian clock synchrony
Here, it is reported that upon UBR4 knock out, more coronin 7 protein is detected, and that overexpression of coronin 7 (fluorescent fusion proteins) restores cargo export from the Golgi
Vietello..Ewald 2021
Front Genet (2021) 12:694033
Lifespan-Associated Gene Expression Signatures of
Recombinant BXD Mice Implicates Coro7 and Set in Longevity
In this report a correlation between increased levels of coronin 7 and longevity is reported
Park..Chung 2021
J Biol Chem (2021) 296:100040
CORO7 functions as a scaffold protein for the core kinase complex assembly of the Hippo pathway
Park et al. show that in MDA-MB-231 carcinoma cells in which coronin 7 is silenced, activation of Hippo signalling is delayed, and that (FLAG-)coronin 7 can be co-immunoprecipitated with components of the Hippo pathway.
Bhattacharya..Rastetter 2016
Sci Rep (2016) 6:25411
Novel Coronin7 interactions with Cdc42 and N-WASP regulate actin organization and Golgi morphology
In this paper it is reported that coronin 7 interacts with Cdc42 and N-WASP; furthermore, the paper shows that mouse embryonic fibroblasts lacking coronin 1 show an altered Golgi morphology
Ericksson..Schioth 2015
BMC Neurosci (2015) 16:13
Implication of coronin 7 in body weight regulation in humans, mice and flies
In this work, data are shown that in mice, coronin 7 expression in the hippocampus is modulated by diet
Yuan..Chen 2014
Mol Cell (2014) 54:586-600
K33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein Trafficking
Yuan et al. report on polyubiquitination of recombinantly expressed FLAG-tagged coronin 7. Further, in contrast to earlier reports (Rybakin..Hasse 2004, PMID: 15327992) these authors show co-immunoprecipitation of actin with (Flag-)coronin 7.
Watanabe..Yamamoto 2010
FEBS Lett (2010) 585:65-70
Coronin7 forms a novel E3 ubiquitin ligase complex to promote the degradation of the anti-proliferative protein Tob
In this work, coronin 7 was found as an interactor of Tob a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. Further, overexpression of (FLAG-)coronin 7 in COS7 cels resulted in proteasomal degradation of Tob.
Rybakin..Clemen 2008
Cell Mol Life Sci (2008) 65:2419-30
Molecular mechanism underlying the association of Coronin-7 with Golgi membranes
This work analyses phosphorylation of coronin 7 by Src kinase in vitro, and that a role of phosphorylation in coronin 7 localization to the Golgi
Rybakin..Noegel 2006
J Biol Chem (2006) 281:31070-8
Crn7 Interacts with AP-1 and Is Required for the Maintenance of Golgi Morphology and Protein Export from the Golgi
Here it is reported that coronin 7 silencing in HeLa and Vero cells affects Golgi morphology
Rybakin..Hasse 2004
FEBS Lett (2004) 573:161-7
Coronin 7, the mammalian POD-1 homologue, localizes to the Golgi apparatus
This paper reports the cloning and tissue expression of coronin 7 as well as its subcellular localization where it is predominantly present in the cytosol as well as within the Golgi region. The paper also reports a failure to co-localise coronin 7 with actin.