Mammalian Coronin 4
Authors
Journal
Title
PMID
Main point related to coronin
Tang..Zhao 2025
Transl Cancer Res 14:7071-7088
Constructing an immune-related prognostic model and exploring the function of HMGB3, TNFSF4, and CORO2A in breast cancer
Analysis of TCGA database for immune-related genes defines coronin 4 as one of the candidates for a prognostic model
Lv..Zhao 2025
Disc. Onc. 16:816
Effects of Coronin 2A on prognosis and immune microenvironment in tumor patients: a knowledge map of the novel biomarker via bioinformatics analysis
Analysis of multiple expression database for immune-related genes defines coronin 4 a potential biomarker
Dhawan..Caplan 2022
Mol Biol Cell (2022) 33:ar107
Coronin2A links actin-based endosomal processes to the EHD1 fission machinery
In this paper, coronin 4 was detected to interact with the ATPase Eps15 Homology Domain Protein 1 (EHD1), and silencing of coronin 4 to result in reduced clathrin-dependent endocytosis
Kase-Katu..Seki 2021
Int J Mol Sci (2021) 22(23):12684
Molecular Pathogenesis of the Coronin Family: CORO2A Facilitates Migration and Invasion Abilities in Oral Squamous Cell Carcinoma
Based on correlation and siRNA analysis this study reports that aberrant expression of coronin 4 facilitates the malignant transformation of OSCC cells
Deng..Wang 2020
Front Oncol (2020) 10:916
Effects of CORO2A on Cell Migration and Proliferation and Its Potential Regulatory Network in Breast Cancer
Here, coronin 4 was found to be overexpressed in breast cancer and that coronin 4 RNAi-mediated silencing reduces cell migration, cell viability, and colony-formation
Lim..Baek 2016
Oncotarget (2016) 7:34759-72
Ubiquitin specific protease 19 involved in transcriptional repression of retinoic acid receptor by stabilizing CORO2A
This study identifies coronin 4 as an interactor of ubiquitin-specific protease 19 (USP19)
Rastetter..Clemen 2015
BMC Cancer (2015) 15:638
Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling
This paper reports that coronin 4 is localised in the cytoplasm and nucleus, is upregulated in colon tumour samples and that GFP-coronin 4 can be phosphorylated in vitro by MAPK14
Huang..Glass 2011
Nature 4 (2011) 70:414-8
Coronin 2Amediates actin-dependent de-repression of inflammatory response genes
Here, Huang et al. show that endogenous coronin 4 localises almost exclusively within the nuclei, and that siRNA-mediated coronin 4 silencing modulates inflammatory response genes.
Marshall..Bear 2009
J Cell Sci (2009) 122:3061-9
Coronin 2A regulates a subset of focal-adhesion turnover events through the cofilin pathway
In this study GFP-coronin 4 is shown to localise within the cytoplasm, but not the nuclei, of MTLn3 cells, a mammary adenocarcinoma cell line, and that its depletion reduces motility, focal adhesion sizes and increases the levels of phospho-cofilin
Yoon..Wong 2003
EMBO J (2003) 22:1336-46.
Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1
Here, coronin 4 was identified in nuclear extracts from HeLa cells by mass spectrometry as a component of the nuclear co-repressor complex N-CoR
Zhafiropoulos..Toftgård 1996
DNA Cell Biol (1996) 15:1049-56
cDNA Cloning of a Novel WD Repeat Protein Mapping to the 9q22.3 Chromosomal Region
This is the first report on cloning and analysis of the gene encoding for coronin 4, and shows it is expressed in epidermis, lung, placenta, brain